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once receptors are saturated, adding more is simply wasteful

1a, comparison of 19,972 protein-coding genes identified a large number of DEGs between recurrent and non-recurrent tumors, highlighting substantial transcriptomic differences associated with recurrence

The role of ROS as a pathological player has been reported in various other cancers including astrocytic and ependymal glial tumors 68 , colorectal cancer 69 , kidney tumor 70 and breast cancers 71