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If the damage goes on long enough, parietal cells can be lost entirely.[ref] Antibodies to parietal cells are found in 90% of patients with autoimmune gastritis

The frequency of B12 shots varies depending on individual needs and the purpose of usage

Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaenovi I, Lastra RR, Curtis M, Yamada SD, Perets R, Mcgregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel E (2019) Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

Ur Rasheed MS, Tripathi MK, Mishra AK et al (2016) Resveratrol protects from toxin-induced Parkinsonism: plethora of proofs hitherto petty translational value

That paper reported no genotoxic findings across an Ames test, a chromosomal aberration assay, and a bone micronucleus assay in rodent models