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Such synergistic approaches, combining complementary methodologies, are crucial for a holistic understanding of redox dysregulation, facilitating the identification of reliable biomarkers, and guiding the development of more effective, targeted antioxidant therapies to improve clinical outcomes in CF

ROS induce dynamic oxidative post-translational modifications on cysteine residues, serving as redox switches to regulate protein conformation, signaling, and cellular homeostasis (11)

Losing excess weight and cutting down accumulated body fat is not only relevant for aesthetic body shape but being overweight and obese accounts for several cardiovascular and cardiometabolic disorders such as hypertension, coronary artery disease, diabetes mellitus, etc

Such alterations disrupt the integrity of fronto-striatal circuits, critical for behavioral regulation, thereby contributing to the hallmark symptoms of hyperactivity, impulsivity, and inattention (145, 146)

37 , e100241 (2018)