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Interestingly, mediating oxidative stress is perhaps one of a few disease presentations with completed or ongoing clinical trials investigating dietary supplements (both NR and MitoQ among others) as the therapeutic strategy

2003 "BPC-157 attenuated COX-2 and NF-B expression in rodent soft-tissue inflammatory models." Chang et al., Molecules 2020 "Systemic BPC-157 improved mucosal integrity in NSAID-induced gut permeability models." Sikiric et al., Curr

One pharmacy was ordered to pay a fine of over $1.7 million for distributing the first drug of this kind without proper approval

Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, et al

The Journal of nutritional biochemistry.Dec 2013;24(12):2076-2084