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Group Comparisons at Week 8 : Group 1 (topical and oral placebo) MI: 385.69 94.38 Group 2 (topical GSH, oral placebo) MI: 330.69 87.90 Group 3 (oral GSH, topical placebo) MI: 347.00 81.77 Group 4 (topical and oral GSH) MI: 314.35 70.13 P - values for Group Comparisons : Group 1 vs Group 2: P = 0

10.1007/s12035-023-03499-1 93 LiY.LiuA.ChenK.LiL.ZhangX.ZouF.et al (2024d)

doi: 10.1155/2013/940603

The clinician's value is precisely the judgment to tell those situations apart, to support the body where support is enough, and to escalate to established treatment when it isn't

As shown in Supplementary Figure 2c, the standard deviation of the replicates for the majority of peptides was low, thus justifying the use of the median oxidation ratio only for Significance B evaluation (see Supplementary Note 1) to determine significantly modified peptides