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Cureus 14 , e33160 (2022)

It binds to the antioxidant glutathione, enhancing the production of ROS, and leading to inflammation and mitochondrial damage [42, 43]

[DOI] [PubMed] [Google Scholar] 112.Zhuang J., Nie G., Hu R., Wang C., Xing C., Li G., Hu G., Yang F., Zhang C

In murine models, elevated TST expression in adipocytes has been shown to confer protection against obesity and T2DM [87]

This dosing is based on several assumptions: glutathione stores are at less than 30% of normal, overdose levels peak at 4 hours, and no further absorption occurs after the initial overdose Range of final hourly infusion= [APAP]/32 to [APAP]/16