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Nifedipine, cyclosporin, carbamazepine and phenytoin may modulate pharmacokinetics of chemotherapy agents and, in turn, the incidence of CIPN, although this evidence stems from case reports (Kandula et al., 2016)

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These effects accelerate wound closure and strengthen the structural integrity of repaired tissue 1,2

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Early studies have shown that continuous subcutaneous injection of MG (0.2 mL/dose, 10 mg/mL twice a week for 10 weeks) induced tumor formation in rats, with a tumorigenicity rate of 22.22% ( Figure 2 Table 1 The pro-cancer manifestations of MG/AGEs in vivo and in vitro