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Advancements in extracellular vesicles biomanufacturing: a comprehensive overview of large-scale production and clinical research

Reduced MTHFR levels and activity means that the one-carbon pathway stalls

Lipocalin-2 (LCN2), derived from immune cells, is upregulated in inflammatory states, but its function depends on the cell source: epithelial-derived LCN2 protects the barrier, while immune-derived LCN2 may promote inflammation [82]