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References Valente, E

J Toxicol Environ Health B 8:3969

Increased proteolytic degradation of aggregated polysaccharides and a rise in non-aggregated proteoglycans are early degenerative modifications in intervertebral discs (Zhang et al., 2021)

Although participants completing the FFQ are assumed to provide accurate and honest responses, it is often difficult for them to recall their dietary intake over extended periods, such as one month

GSH can also serve as a substrate for S-glutathionylation of proteins in the presence of small redox enzyme glutaredoxins (GRX), which also utilizes GSH as a cofactor ( Figure 1 )