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Moreover, mitochondria can modulate their morphology and regulate their number, size and position within the cytoplasm by two opposite processes, i.e., mitochondrial fission and fusion [103]

Long-term metformin therapy reduces both steroidogenic and metabolic enzyme activities in the ovaries and the adrenal response to adrenocorticotrophin (ACTH), helping mitigate hyperandrogenism in women with PCOS (Lan et al., 2015

developed quercetincopper nanoparticles with strong antioxidant and antibacterial activity, which effectively reduced weight loss and extended the shelf life of Shine Muscat grapes (Che et al., 2025)

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However, the regulatory mechanism of ferroptosis has not been fully elucidated and the investigation still faces challenges