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Compared to the general population, pregnancy outcomes in RA patients are often unsatisfactory, particularly in those with high disease activity 46

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However, there is a chance that patients will develop iron deficiency

SI exerts its anti-inflammatory effects by targeting immune cells, including macrophages and neutrophils, thereby regulating the release of inflammatory cytokines such as TNF-, IL-6 and IL-1 to control the inflammatory response (Wang et al., 2022), such as NF-B, ERK, and IB signaling pathways