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The calcaneal bone was fixed in a custom-made clamp at 30 dorsiflexion, relative to the direction of traction, as described previously [14, 15]

Peer review Peer review information Nature Communications thanks Jos Pedro Friedmann Angeli and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

In a phase I study conducted in Japan including 12 human participants (2036 years), daily consumption of 100 g fresh broccoli sprouts was shown to improve HDL by 7.6% in female participants and reduce total cholesterol by 10% in male participants from baseline measurements (Murashima et al., 2004)

Recent aspects of the effects of zinc on human health

All three components fall within the optimal molecular weight range (418900 Da) for efficient nasal mucosal absorption and direct nose-to-brain delivery, with each component independently studied for CNS penetration and neuroactive signaling