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Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness

Chang JY , Dong L, Mohan R, Liao L, Cox JD, Komaki R

Preclinical and early clinical strategies that deplete MDSCs, block their recruitment, inhibit key metabolic pathways, or reprogram them toward differentiation have shown promise in restoring T-cell activity and improving responses to checkpoint inhibitors and other therapies (8)