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Rome, Italy: 2015

Aggrephagy Aggrephagy involves a routing of protein aggregates, which are unable to be degraded by proteasomes owing to their size or generation rate, to lysosomes via specific SARs (Cppola-Segovia and Reggiori, 2024)

Tetrandrine citrate suppresses breast cancer via depletion of glutathione peroxidase 4 and activation of nuclear receptor coactivator 4-mediated ferritinophagy

The goal is modified activity that allows healing while preventing deconditioning and stiffness

The use of small chemical inhibitors or monoclonal antibodies such as bevacizumab and cetuximab to target RTKs has shown effectiveness in cancer treatment, and thus, comprehending the intricate mechanisms of RTK regulation is of clinical significance (11,12)