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The cells were incubated with 70% ethanol at 20 C overnight

3.4 Selenium and prostate cancer Prostate cancer ranks as the second most common male malignancy globally and holds the top position in the United States (100)

Moreover, following oral administration, many TCM components, especially those with low oral bioavailability like polyphenols, flavonoids, polysaccharides, and saponins, are not fully absorbed in the gastrointestinal tract[107]

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Treatment of A549 and HCC827 cells with the food additive ferric ammonium citrate (AFC) for 24 h resulted in a significant decrease in the expression of cell proliferation-related proteins (Ki67, CDK2 and CCND), autophagy-related proteins (ATG3 and LC3A/B) and ferroptosis negative regulators (GPX4 and FTH1), followed by a decrease in intracellular autophagy and induction of cellular ferroptosis [188]