glutathione reduction biochemistry - an overview Overview of de novo glutathione

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Our SAR analysis demonstrated that the nitro moiety is essential for the anti-proliferative and enzymatic inhibition activities of LCS3, suggesting that the electron-accepting properties of the nitro group confer intermolecular affinity for the reductases GSR and TXNRD1, which are electron donors to GSSG and thioredoxin substrates

Wabitsch, M

The mean GSH content measured in the bone marrow at the two timepoints was 2.24 +/- 0.21 nmol mg-1 protein, range 0.91-4.19 nmol mg-1 protein