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A recent study found that co-administration of Rapamycin-loaded poly(lactic acid) (PLA) nanoparticles (SVP(Rapa)) with AAV vectors prevents the formation of neutralizing antibodies and enables successful vector re-administration in mice and nonhuman primates in an antigen selective manner, in addition to allowing for repeat dosing of AAV vectors to increase expression of a transgene in the liver

Springer, Berlin Ahmad P, Ozturk M, Gucel S (2012) Oxidative damage and antioxidants induced by heavy metal stress in two cultivars of mustard ( Brassica juncea L.) plants

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Therefore, these compounds could find application to treat diabetes in animals

Lipopolysaccharide (LPS) produced by dysbiotic bacteria inhibits this enzyme, again reducing T4 to T3 conversion