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Several other studies have demonstrated the safety of this method [322, 324, 326, 327]

Finally, we found that PA increased the Fe 2+ content and that CD36 overexpression accentuated this effect, which could be abrogated by DFO (Fig

Effects of lloprost and pentoxifylline on renal ischemia-reperfusion in rabbit model

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For example, copper ions can lead to GSH depletion through two mechanisms: the direct downregulation via the redox reaction between Cu 2+ and intracellular GSH, and the activation of a Fenton-like reaction by generating Cu + to amplify oxidative stress ( in situ GSH in tumor triggered mCMSNs biodegradation and reduced Cu 2+ into Cu + for enhanced hydroxyl radical production, leading to a powerful inhibition effect on tumors (Liu et al., 2019)