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Description

To test this, we first developed an acute hyperuricemia mouse model by injecting uric acid intraperitoneally to rapidly elevate blood UA levels

Signal Transduct Target Ther 6:94

23 ) orthotopic patient-derived xenografts of IDH-mutant glioma to continuous infusions of amide- 15 N-glutamine, 15 N 2 -uridine or saline and performed conventional and spatial metabolomics on brain tissues (Fig