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Despite remaining challenges in purification efficiency and batch standardization, these features collectively establish PDEVs as a promising, scalable, and low-immunogenic nanotherapeutic platform, rather than just an experimental delivery system

[5] Beyond its antioxidant properties, ALA may serve as an essential cofactor for mitochondrial enzymatic complexes (notably the -ketoacid dehydrogenases) involved in oxidative metabolism

10.2144/fsoa-2019-0074 Future Sci

These mutations occur in LS carcinomas at higher frequencies than in precursor lesions and include those found in genes associated with proinflammatory and metabolism pathways [66]