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Moreover, ascorbate promotes the synthesis and activation of antioxidant enzymes, like SOD, CAT, and GPx, and it enhances transcription factors, like Nrf2, redox factor-1 (Ref-1) and activator protein 1 (AP-1), which regulate antioxidant gene expression [217]

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Although anticipating academic failure, Cass succeeds at enrolling in Trinity College Dublin with Elaine, where Cass quickly grows tired of Elaine's narcissism and selfishness