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To contextualize the need for this integrative approach, Table 1 provides a concise comparison including benefits and drawbacks between existing diagnostic and therapeutic frameworks, and the added mechanistic value offered by the proposed workflow (De Strooper and Karran, 2016

doi: 10.12669/pjms.334.12571 189

10.1016/j.psyneuen.2016.11.031 Psychoneuroendocrinology 53 LiuX.PingS.GaoW

Sequelae of untreated venous insufficiency

Neuroinflammation and oxidative stress are two interlinked pathological processes that play a significant role in the onset and progression of numerous neurological disorders