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Vitamin B12 deficiency can lead to a range of symptoms including fatigue, weakness, pale skin, shortness of breath, numbness or tingling in the hands and feet, and cognitive issues, such as memory loss or difficulty concentrating

Long-term clinical trials are needed to assess the safety and efficacy of these interventions in different patient populations and stages of neurodegenerative diseases

Another study that focused on identifying ALS biomarkers found that the deglutathionylating enzyme human GSTO1 was significantly reduced in peripheral blood mononuclear cells and spinal cord cells of sALS patients 147

A small needle is used, and the procedure is over in seconds

In a few studies, the oral form has also effectively reduced dark spots and achieved skin lightening