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A bunch of studies from 2012 "confirms the ability of copper peptides to improve aging skin conditions, which make them indispensable in anti-aging and protective cosmetic products." Several research theories suggest that "bioactive peptides hold great potential for cancer therapy and diagnostics." Thereby indicating that peptides are safe for topical use

Autophagy and apoptosis cascade: which is more prominent in neuronal death

10.1038/s41575-020-00381-6 33 KeY.LiD.ZhaoM.LiuC.LiuJ.ZengA.et al (2018)

The molecule showed a time-dependent effect, with 50% inhibition of cell growth at 72- and 96-h exposure

Next, we assessed the cross-reactivity of SCG101 with human peptides and potential off-target activity