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The Energy Metabolism Dysfunction in Psychiatric Disorders Postmortem Brains: Focus on Proteomic Evidence

Transl Psychiatry 7 , e1215 (2017)

found that an engineered alternative scaffold protein [affibody molecule (Z FcRn )] effectively blocked the IgG-FcRn interaction when repeated injections of Z FcRn and Z FcRn fused to an albumin binding domain (ABD) in mouse models led to a 40% reduction of IgG in serum (88)