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Also, heat tolerance induced by Glu was impaired by exogenous CaCl 2 (may produce Ca 2+ overloading), LaCl 3 (plasma membrane Ca 2+ channel blocker), EGTA (Ca 2+ chelator), as well as trifluoperazine and chlorpromazine (calmodulin antagonists) ( 2 ) ( Drought Stress Drought stress caused by the decline in soil water potential interferes with many physiological processes at different levels, such as water uptake, transpiration, photosynthesis, seed germination, plant growth, and development ( For land plants, stomata is indispensable structure to control water balance and gas exchange, its movement is regulated by a coordinated action of a series of signaling molecules, such as Ca 2+ , ROS, NO, H 2 S, and ABA ( Arabidopsis and fava bean ( Vicia faba L.), Glu treatment increased [Ca 2+ ] cyt in guard cells, which in turn led to stomata closure

Circulation: Heart Failure, 17 (4), Article e011351

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When this barrier is disrupted, RPE cell activation occurs, leading to the proliferation, epithelial-mesenchymal transition (EMT), and secretion of extracellular matrix molecules, thus promoting vitreoretinal disorders, including proliferative vitreoretinopathy (PVR), age-related macular degeneration (AMD), and proliferative diabetic retinopathy (PDR) [1,2,3]