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WangCZhouJWangJLiSFukunagaAYodoiJet alProgress in the mechanism and targeted drug therapy for COPD

PI3K/Akt/mTOR Signaling The two primary signaling pathways activated by IGF-1 DES through IGF1R are the PI3K/Akt/mTOR axis and the Ras/Raf/MEK/ERK MAPK cascade, both of which drive anabolic processes, cell survival, proliferation, and metabolic reprogramming

Modeling clinically heterogeneous presenilin mutations with transgenic Drosophila

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