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However, chronic overexpression of fatty acid metabolism has been shown to reduce Ca 2 uptake, promote LV hypertrophy, impair systolic function, and increase the cardiac injury markers, all of which contribute to long-term cardiac dysfunction and remodeling [2]

Analysis of metabolic network pathway also corroborates these conclusions (Figure 7C)

[DOI] [PMC free article] [PubMed] [Google Scholar] Allen D.E., Gellai M

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Arabinoxylans (PPCP-1) isolated from the bark of Phedendron chinense Schneid were shown to downregulate the expression of AGEs receptors induced by streptozotocin in the tibia of diabetic rats, thereby improving diabetes-associated osteoporosis (Wang et al., 2021)