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Centella is widely used because it is effective at low percentages

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In the event of IBDs, the relevance of polyphenols has been described in previous literature, exerting their benefits in this condition by many different mechanisms including the reduction of epithelial damage, inflammation, hemorrhage, oxidative stress, gut dysbiosis, apoptosis, gland dysfunction, bloody stools, and ulcerations while promoting an increase in mucin content, number of crypts and reinforcing the integrity of the epithelial barrier [47]