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Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (marketed as Mounjaro) and chronic weight management (marketed as Zepbound)

An unexplained phenomenon in rodent models of AP-induced weigh gain is that only females gain weight when treated with APs 48,49,50

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