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This change is explained by the role of inflammation in promoting the microbiota [40]

In a 2021 systematic review and meta-analysis published in the Journal of Personalized Medicine , Daniel Rossignol and Richard Frye examined the FRAA literature and found that children with autism are roughly 19-fold more likely to be FRAA-positive than typically developing children, with FRAA prevalence in autism reaching well above half of children studied across multiple cohorts [2]

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