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Clinical laboratories generally define vitamin B12 deficiency as a serum level below 148 pmol/L (approximately 200 pg/mL)

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Circular dichroism spectroscopy To analyse the secondary structure content and thermal stability of ROXY9 and GRXC2, far-UV spectra and thermal unfolding data were collected using circular dichroism spectroscopy (Chirascan, Applied Photophysics)

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95% confidence interval [CI], 0.310.69

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Methods: Data of patients hospitalized between 2012 and 2021 with at least one ICD-10 code of cirrhosis and / or HCC were extracted from the French national medicalized information system program

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