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Effects of L-carnitine over-supplementation on spermatogenesis and sperm function in healthy NMRI mice

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(2021) recently reviewed six randomized controlled trials that estimated the effect of betaine supplementation (at least 4 g/day) in adults for a maximum of 24 weeks on blood lipids and found that total cholesterol was increased moderately, but there was no significant effect on plasma LDL and HDL cholesterol or TG levels