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NLRP3 activation, on the one hand, eliminates damaged mitochondria by triggering mitophagy [208], and, on the other hand, participates in the mutual regulation between pyroptosis and autophagy by regulating the ROS-AMPK-mTOR axis [209]

BPC-157 constitutes 62.5% of the total 80mg blend by mass, reflecting both its studied dose-dependency in preclinical models and its relatively higher molecular weight (~1,419 Da) compared to KPV (~340 Da) and GHK (~340 Da)