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However, when multiple active sites differ in their ability to bind or convert substrates, or when interactions such as allosteric effects, cooperativity, or competitive adsorption occur between active sites, the resulting v -versus-[S] curve deviates from the standard hyperbolic function, displaying atypical kinetics

Additionally, D-NAC was shown to be more effective than NAC in bypassing the cysteineglutamate antiporter (Xc-) for cell uptake, increasing the GSH levels while preventing both glutamate release and excitotoxicity in mixed glia derived from Mecp2-null mice, a model of Rett syndrome

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Characterization of the content of protein, NADPH-cytochrome P450 reductase, and cytochromes P450 and bs in HLM preparations Protein concentrations in microsomal suspensions were determined by the bicinchoninic acid assay

Norden E, Heiss EH