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Furthermore, quercetin could enhance increased Keap1/Nrf2 levels and increase the antioxidant capacity of HBMECs, significantly down-regulate AFT6/GRP78 protein, interdict ER stress, and protect HBMECs from H/R damage

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The development of depression-like behavior is consolidated by IL-6-induced activation of locus coeruleus neurons and IL-1beta-induced elevated leptin levels in mice