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Paeoniflorin significantly increased melanin content and intracellular TYR activity of human melanocytes by regulating the ERK/CREB pathway, and improved monobenzone-induced vitiligo in mice [82]

Canadian users should understand they are self-administering an unapproved substance, accepting personal responsibility for any outcomes

Maintenance Phase: Once the desired skin tone is achieved, maintenance doses (usually once every 2-4 weeks) help sustain results

Dispense a moderate amount and lather up with a small amount of water

Furthermore, moisture and humidity can accelerate hydrolysis, breaking down peptide bonds and leading to fragmentation