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PMID: 16502665

In acute gout, MSU crystals, liberated from tissue deposits by remodeling effects or microtrauma, stimulate inflammatory cascades that involve complement activation and assembly of the C5b-9 membrane attack complex, and release of multiple inflammatory cytokines, including IL-1 and the chemokines IL-8 (CXCL8) and GRO- (CXCL1)

[,] When it comes to depression that is resistant to medication, NACs anti-inflammatory properties might be especially significant

D., Lonardo, A., Zoppini, G

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