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It also activates proteins known as sirtuins that regulate DNA repair and cellular longevity

The list includes: Addisons disease Amyloidosis Ankylosing spondylitis Coeliac disease Crohns disease Dermatomysositis Graves disease Guillain-Barre syndrome Hashimotos thyroiditis Multiple sclerosis (MS-like presentation/SACD (subacute combined degeneration)) Myasthenia gravis Pernicious anaemia/B12 deficiency Reactive arthritis Restless leg syndrome (RLS) Rheumatoid arthritis Sjogrens syndrome Systemic lupus erythematosus Type 1 diabetes Ulcerative colitis Many of the above conditions have overlapping symptoms, for example fatigue, general ill-feeling, joint pain and rash

Off-label means a treatment is used in a way not specified in the FDAs approved labeling