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The increased inositol-requiring enzyme 1 expression by PFOS, which indicated endoplasmic reticulum (ER) stress activation, was associated with PFOS-mediated autophagy activation that could be attenuated through 4-phenylbutyrate (5 mM, an ER stress inhibitor) and l-Carnitine pretreatment

FukudaSSongJKMaharaKKuwakiHJangJYTakeuchiMet alBasal left ventricular dilatation and reduced contraction in patients with mitral valve prolapse can be Secondary to annular dilatation: preoperative and postoperative speckle-tracking echocardiographic study on left ventricle and mitral valve annulus interaction

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Chromatin remodeling involves structural changes such as DNA methylation, histone methylation, and acetylation, which greatly impact transcriptional changes of different genes