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Ethical Statement Animal experiments were carried out in accordance with the European Communities Council Directive of November 24, 1986 (86/609/EEC), revised in 2010 (2010/63/EU), regarding care of laboratory animals in an AAALAC-accredited facility following acceptance of the study design by the Institute of Lab Animal Science (Chinese Academy of Science, Beijing, China) IACUC for experiments conducted on non-human primates

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No human study has tracked cancer incidence following BPC-157 administration, leaving the oncological risk profile unresolved and requiring cautious evaluation before use in individuals with active or prior malignancies