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Additionally, it may minimize heme breakdown in the spleen and increase the lifespan of red blood cells, leading to higher hemoglobin levels 22

A notable double-blind RCT in 262 elderly subjects found that NAC (600 mg twice daily) for 6 months significantly reduced influenza-like episodes only 25% of NAC-treated subjects who seroconverted to influenza A developed clinical symptoms, compared to 79% of placebo subjects (De Flora et al., Eur Respir J, 1997) [40]

doi: 10.1016/j.jcis.2024.02.018 68 YilmazF

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22 Hepcidin is encoded by the HAMP gene, and is upregulated by a lot of influence factors, such as bone morphogenetic protein (BMP), hemojuvelin (HJV) as well as human hemochromatosis protein (HFE), which regulating both the TFR and the BMP receptor on hepatocytes