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Limitations of traditional mechanistic frameworks Traditional models of CVD-cognitive impairment comorbidity primarily focus on vascular-mediated processes, including cerebral hypoperfusion, where arterial stenosis or HF-induced reduction in blood flow impairs the delivery of oxygen and nutrients to neurons

We have proposed that certain molecules that contain an imidazole ring, particularly one with a high pKa, may be able to permanently sequester deuterium, helping to reduce the deuterium burden in mitochondria (Seneff et al., 2025a)

Oral supplements are a common and convenient way to boost vitamin intake

10.1016/j.yexcr.2021.112800 Exp Cell Res

References: EMC Summary of Product Characteristics for acetylcysteine injection (UK)