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The therapeutic effects of AB4 on SALI were evaluated through histopathological examination, biochemical analysis, immunofluorescence staining, and Western blotting, which collectively elucidated its in vivo and in vitro mechanisms of action

The involvement of these peroxidases in the detoxification of H 2 O 2 is further corroborated by the upregulation of their respective transcripts following exposure to 20 mM H 2 O 2 (Fig

Ling J et al (2022) The extracts of dendrobium alleviate dry eye disease in rat model by regulating aquaporin expression and MAPKs/NF-B signalling

Joyal JS, Sun Y, Gantner ML, Shao Z, Evans LP, Saba N, et al

Despite the limited research available on the interplay between mitochondria and iron overload, their critical function in maintaining iron homeostasis and managing associated damage underscores their importance in the pathological processes of both congenital and acquired iron overload