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In population genetics, a polymorphism refers to a DNA sequence variation where two or more alleles exist at a frequency of at least 1%

136 Since EAAT2 plays a central role in synaptic plasticity and neurotransmission, disruption of the metabolic and structural complexes in microdomains that enable EAAT2 clearance of glutamate suggests a role for atypical transporter localization in the pathophysiology of brain diseases

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Table 1: GSH content of rat liver determined by spectrofluorimetric assay method Conclusion The new spectrofluorimetric assay method for GSH and glutathione transferase activity using monobromobimane (MBB) could among other methods be used as a sensitive and specific research tool for biochemical studies of drug metabolism and drug toxicity