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This tumor disrupts the glands normal function, leading to excessive production of adrenocorticotropic hormone (ACTH), which in turn stimulates the adrenal glands to produce excessive cortisol

In addition to the rapid and long-lasting antidepressant response, boosting mitochondrial metabolism of LAC leads to the amelioration of specific cognitive domains [46, 47], and promotes behavioral resilience at the social defeat stress (SDS) paradigm [27]

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This type of study is less accurate than a clinical trial, and can only find correlations by design