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HppA-driven proton extrusion and restoration of the proton-motive force involves an additional energy expense through pyrophosphatase hydrolysis (Belogurov and Lahti, Similarly, the H + /Cl antiporter ClcA involved in adaptation to chloride stress affords chloride efflux at a cost for the proton-motive force

Simultaneous inhibition of caspases by Z-VAD-FMK (Z-VAD) blocks apoptosis and causes necroptotic cell death (Fig

Am J Physiol-Cell Physiol

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In this way, glutathione helps to prevent damage and lowers the risk of heart attacks