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Important note: Although oral therapy is very effective, the treatment of a severe deficiency with pronounced neurological symptoms should always be carried out in close consultation with a doctor

The team found that greater weight regain at the end of the study was associated with greater reversal of improvements not only in weight, but also in measures including waist circumference, levels of bad cholesterol, blood pressure, and blood glucose levels

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However, headache incidence rates were similar between AOD-9604 and placebo groups, suggesting that many cases represented background occurrence rather than treatment-related effects