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Patients received either pemetrexed 500 mg/m2 intravenously in combination with cisplatin 75 mg/m2 intravenously on Day 1 of each 21-day cycle (n=839) or gemcitabine 1250 mg/m2 intravenously on Days 1 and 8 in combination with cisplatin 75 mg/m2 intravenously on Day 1 of each 21-day cycle (n=830)

Compounded medications are not subject to FDA approval and lack the same safety and efficacy data as FDA-approved commercial medications

When people have been on that for extended periods of time, that has an effect on bone loss

In addition, senescence-targeting should also be evaluated in aging adipose tissue