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44,45 Further investigations have revealed that TRAF2 exhibits a higher binding affinity towards TRADD for signaling, rather than TNFR1, and impedes apoptosis by recruiting inhibitor-of-apoptosis proteins (clAPs)

This activation leads to the conversion of ATP (adenosine triphosphate) to cyclic AMP (cyclic adenosine monophosphate or cAMP)

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